Here are a couple of cases I’ve shown at previous teaching sessions.
This patient has had an orbital mass growing over the last year or so, associated with pain.
In this view we can see a nested tumour with a cribriform (“Swiss cheese”) architecture towards the bottom of the image consistent with adenoid cystic carcinoma.
In the top right of this image, the tumour surrounds a nerve, so the symptom of pain is understandable.
The next patient has had an enucleation for uveal melanoma.
The low power view demonstrates a classic collar stud profile, and the overlying retina is largely obliterated.
Elsewhere in the specimen, the retina is morphologically well preserved, with intact photoreceptors. But a thick layer of tumour cells covers the inner retina, presumably due to intravitreal spread.