Teaching eye pathology
Cornea from an elderly female with gradually deteriorating vision Corneas make up a significant proportion of our workload. Most of our corneal specimens fall into four categories: endothelial failure, dystrophies, infections or interference with vision (eg scarring or ectasia). This specimen is full thickness cornea, with the epithelium on the right and endothelium on the… Continue reading Eye pathology case 8
Enucleation specimen. Intractable raised intraocular pressure due to an iris mass. This is a low power view of the anterior segment (cornea, anterior chamber, iris, ciliary body and a piece of lens). The section is off-centre, and so the iris is continuous rather than having a central gap where the pupil is. The iris is… Continue reading Eye pathology case 7
Biopsy from a young adult with an orbital mass and pain For those of you sitting exams (whether ophthalmologists or histopathologists), this is a classic pattern to recognise. It shows cribriform ("sieve-like") architecture, sometimes compared to Swiss cheese for obvious reasons. There are nests of basaloid tumour cells containing punched-out cystic spaces filled with mucin.… Continue reading Eye pathology case 6
Persistent eyelid lump First, some background orientation. Here's a normal full-thickness eyelid. Epithelium forms a continuous cover of the surfaces, with epidermis at the top and conjunctiva at the bottom. Beneath the epidermis lies skeletal muscle (orbicularis). Deep to that lies the tarsal plate. The tarsal plate consists of dense fibroconnective tissue and the meibomian… Continue reading Eye pathology case 5
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