Eye pathology case 5

Persistent eyelid lump First, some background orientation. Here's a normal full-thickness eyelid. Epithelium forms a continuous cover of the surfaces, with epidermis at the top and conjunctiva at the bottom. Beneath the epidermis lies skeletal muscle (orbicularis). Deep to that lies the tarsal plate. The tarsal plate consists of dense fibroconnective tissue and the meibomian… Continue reading Eye pathology case 5

Eye pathology case 4

Temporal artery biopsies Temporal artery biopsies are submitted when there is a clinical concern about temporal arteritis (also known as giant cell arteritis—GCA—or cranial arteritis). Patients may initially present to the ophthalmologist with sudden and catastrophic visual loss (anterior ischaemic optic neuropathy). They may also have headache or more generalised symptoms such as joint pain… Continue reading Eye pathology case 4

Eye pathology case 3

This is a classic exam-type case for the FRCOphth and similar examinations. The patient is a young adult undergoing a corneal graft. (Click on the images to see them full-sized) This is a low power view. Non-keratinising stratified squamous epithelium covers the convex surface. Beneath it lies Bowman's layer (not readily visible at this power)… Continue reading Eye pathology case 3

Eye pathology case 2

Here's a case that I came across recently. I know I said in my last post I'd concentrate on common or exam-type diagnoses, but this one is a useful clinical pitfall to know about. Young adult with a subconjunctival pigmented area ?melanoma This medium power image shows fibroconnective tissue with no identifiable epithelium. Centrally, there… Continue reading Eye pathology case 2