Eye pathology case 16

I recently received a query as to whether I've come across corneal copper deposition, as we might see in the Kayser-Fleischer ring of Wilson disease. Not sure who Kayser, Fleischer or Wilson were? Here's a little information. There's a nice picture of the clinical appearance and an overview of Wilson disease here. On checking our… Continue reading Eye pathology case 16

Eye pathology case 15

Cornea from a young adult with gradually worsening vision This low power image shows a full thickness cornea with a little artefactual creasing. Remember, the 5 layers are: epithelium, Bowman's layer, stroma, Descemet's membrane and endothelium. The stroma is perhaps a little thinned towards the right of centre, and there is subtle scarring in the… Continue reading Eye pathology case 15

Eye pathology case 11

Middle-aged patient with worsening vision many years after a previous procedure This low power view shows a full thickness corneal button. We've sliced it in two and embedded both halves on our cut surface. It is not obviously inflamed or vascularised (something I specifically mention in my reports as a negative finding). However, there is… Continue reading Eye pathology case 11

Eye pathology case 8

Cornea from an elderly female with gradually deteriorating vision Corneas make up a significant proportion of our workload. Most of our corneal specimens fall into four categories: endothelial failure, dystrophies, infections or interference with vision (eg scarring or ectasia). This specimen is full thickness cornea, with the epithelium on the right and endothelium on the… Continue reading Eye pathology case 8