Eye pathology case 11

Middle-aged patient with worsening vision many years after a previous procedure This low power view shows a full thickness corneal button. We've sliced it in two and embedded both halves on our cut surface. It is not obviously inflamed or vascularised (something I specifically mention in my reports as a negative finding). However, there is… Continue reading Eye pathology case 11

Eye pathology case 8

Cornea from an elderly female with gradually deteriorating vision Corneas make up a significant proportion of our workload. Most of our corneal specimens fall into four categories: endothelial failure, dystrophies, infections or interference with vision (eg scarring or ectasia). This specimen is full thickness cornea, with the epithelium on the right and endothelium on the… Continue reading Eye pathology case 8

Eye pathology case 3

This is a classic exam-type case for the FRCOphth and similar examinations. The patient is a young adult undergoing a corneal graft. (Click on the images to see them full-sized) This is a low power view. Non-keratinising stratified squamous epithelium covers the convex surface. Beneath it lies Bowman's layer (not readily visible at this power)… Continue reading Eye pathology case 3

Microscopy November 2019

During yesterday's microscopy session, we chatted about relative frequency of uveal melanoma in humans vs cats and dogs. I didn't know that certain dog breeds with higher numbers of melanocytes are prone to oral melanomas! Just came across this recent open access review of canine melanomas as potential models for human melanomas: Canine Melanomas as… Continue reading Microscopy November 2019